Novak Djokovic and Rafael Nadal are braced to deliver a potentially fatal blow to Roger Federer's fading hopes of matching Pete Sampras's record of seven Wimbledon wins.
The great Swiss is fighting time as well as an air-tight Grand Slam grip developed by Djokovic, the defending champion, and Nadal, who have won nine of the last 10 majors between them and contested the last four Grand Slam finals.
World number three Federer, who celebrated the last of his record 16 Grand Slam crowns at the 2010 Australian Open, will be 31 in August.
Sampras was 28 when he won the seventh and last of his Wimbledon titles in 2000; Djokovic is still only 25 and Nadal, 26.
It wasn't long ago that Wimbledon represented Federer's traditional bolt-hole, winning five successive championships between 2003 and 2007, then adding a sixth in 2009.
But even in his London safe haven, the shadow of Nadal has loomed large.
The Spaniard, who has just collected a record seventh French Open title, deposed Federer in a five-set epic in 2008, having been runner-up in the two previous years.
Federer's triumph in 2009 came when Nadal was sidelined with a knee injury.
In 2010, Tomas Berdych knocked him out in the quarter-finals while in 2011, the Swiss lost his first ever Grand Slam match from two sets to love up when he was bludgeoned to defeat in the last eight by Jo-Wilfried Tsonga.