Wayne Rooney will miss Manchester United's Premier League clash against Bolton on Saturday after suffering a calf injury on England duty.

Rooney sustained the problem during England's World Cup qualifying defeat against Ukraine last weekend.

United boss Sir Alex Ferguson believes Rooney could be available for Wednesday's Champions League trip to CSKA Moscow, although he may be saved for the crucial Premier League match at Liverpool on October 25.

"Calf injuries can be troublesome," Ferguson said on Friday. "We are trying our best to get him fit for Wednesday but I have my doubts on that. But Wayne should be fit for the Liverpool game.

"We know how difficult these things can be so we will not be taking any chances with the Moscow trip."

There was some good injury news for Ferguson on Friday, however, as he revealed that Dutch goalkeeper Edwin For Van Der Sar is ready to play against Bolton - his first appearance of the season after he broke two fingers during a friendly with Bayern Munich in July.

"Edwin plays tomorrow (Saturday)," Ferguson said. "He had a reserve game 10 days ago and has come through that fine. He has been training for quite a spell now but with a hand injury you don't take any chances and that game has given him a good confidence boost."

Ferguson's decision to recall van der Sar brings to an end an eight-game Premier League run for Ben Foster in which his questionable form earned public criticism from the Scot.

The 26-year-old Foster, who kept a clean sheet in England's 3-0 win over Belarus on Wednesday, is likely to remain on the sidelines for some while if van der Sar suffers no reaction to his injury.

But Ferguson did try to lessen the impact upon Foster by predicting a bright future for him and labelling the youngster as the best English keeper in the game.

"Ben has been outstanding in a lot of things. It was typical, the save he made on Wednesday. He made a fantastic save for us at Wigan at an important time in the game and a fantastic save at Stoke," Ferguson said.

"Those are demonstrations of the guy?s ability but, having said that, he still does not have a lot of game time experience.

"Injuries have curtailed the progress he was making. He has had two cruciates (knee injuries) and been off a long time so I think he is only going to get better.

"I was pleased on Wednesday that he had that kind of performance for England because I still feel he is the best English goalkeeper around."

Van der Sar's return was assured once Foster was held accountable for bad goals conceded by United in recent home games against Arsenal, Manchester City and Sunderland, especially as Ferguson's appreciation for the Dutchman, who turns 39 at the end of the month, could not be greater.

"Edwin and (Peter) Schmeichel have been the best goalkeepers in this club's history as far as I'm concerned," added Ferguson. "We are getting back that calming influence that he has on everyone around him and that is important.

"Of course, Ben has to be patient and I don't think it's a bad thing for him to come out now.

"If Edwin comes through tomorrow (Saturday), he has two important games away from home, at CSKA and at Liverpool so his return couldn?t come at a better time with the experience he's got."

Ferguson also expects England midfielder Owen Hargreaves to return to action in three weeks.

Hargreaves, 28, returned to Manchester last month after spending a year in the United States recovering from surgery on both knees to combat a long-standing tendinitis problem.

"Owen is doing a lot of good work now," Ferguson said. "He is making great progress, which we are very pleased about.

"It is not a thing you have to rush because he has been out a year. We have to monitor it a bit more closely but he is giving us good signs.

"He should be back in the first-team level in three weeks from now, easily."